Characterization of renal biopsies performed at the Adult Nephrology Department of the Hospital de Clínicas
DOI:
https://doi.org/10.70108/nefrologiapy.2023.1.1.18Keywords:
kidney biopsy, nephrotic syndrome, lupus, transplantAbstract
Introduction: Biopsy is an important diagnostic technique for the treatment of patients with kidney disease. It is possible to make an etiological diagnosis, in addition to determining the prognosis and the probability of response to treatment.
Objective: Determine the main indications and the most frequent histopathological findings in renal biopsies performed in the Department of Adult Nephrology of the Hospital de Clínicas from April 2016 to November 2022.
Methods: Observational, retrospective, cross-sectional study.
Results: 130 biopsies were performed in the period studied, 50.7% in female patients. The main reasons were: nephrotic syndrome 34.6%, systemic lupus ery- thematosus 31.5% and transplant patients with suspected rejection 18.4%. The following most frequent histopathological diagnoses were obtained according to the different indications: focal and segmental glomerulosclerosis-FSGS (24), stage IV lupus nephritis (24) and graft rejection (16), respectively. 0.7% of patients pre- sented nephrectomy as a complication and retroperitoneal hematoma in an equal percentage.
Conclusion: 130 renal biopsies were performed, with no important difference between sexes. The main indications were: nephrotic syndrome, systemic lupus erythematosus and suspected graft rejection, with the most frequent histopathological diagnoses being FSGS, stage IV lupus nephritis and rejection, respectively. Complications occurred in 1.4%.
Downloads
Metrics
References
(1) Rivera M. Biopsia renal ecodirigida. Nefrologia 2010;30(5):490-2.
(2) Fogo AB, MD. Core curriculum in Nephrology: Approach to Renal Biopsy. Am J Kidney Dis 2003;42:826-36.
(3) De León-Bojorge B. La biopsia en el diagnóstico de la enfermedad pediátrica. Acta Pediatr Mex 2009;30(1): 36-53.
(4) Carrilho P. Indicações actuáis para biópsia renal. Acta Méd Port 2005; 18: 147-151.
(5) Peces R, de Sousa E, Peces C. La biopsia renal en situaciones especiales. Nefrologia 2011;31(6):627-9.
(6) Appel GB. Renal biopsy: How effective, what technique, and how safe. J Nephrol 1993; 6:4.
(7) Castro R, Sequeira MJ, Faria MS, Belmira A, Sampaio S, Roquete P, Silvestre F, Rocha C, Morgado T. Biópsia renal percutânea: Experiência de oito anos. Acta médica portuguesa 2004; 17: 20-26.
(8) Bacallao R, López L, Llerena B, Heras A, Dávalos J, Gutiérrez F, González L, Magrans Ch. Experiencia de 20 años en biopsia renal percutánea en adultos del Instituto de Nefrología. Revista Cubana de Investigaciones Biomédicas. 2015; 34(3):213-223.
(9) Valjalo R, Mallea MT. Caracterización de enfermedades glomerulares: análisis de 22 años de biopsias renales. Rev Med Chile 2023; 151: 52-60.
(10) Liderman, S. Registro Argentino de biopsias renales. Reporte de situación en Capital Federal y Gran Buenos Aires a abril del 2008. Revista de nefrología, diálisis y transplante, vol. 28, núm. 2, abril-junio, 2009, pp. 55-60. Sociedad Argentina de Nefrología. Buenos Aires, Argentina.
(11) Rodrigues MJ, Teixeira R. Aspectos clínico-patológicos de pacientes submetidos á biópsia renal. Revista Paraense de Medicina V.20 (3) 2006; 15-22.
(12) Becerra-Pino I, Guerrero-Avendaño G, Enríquez-García R. Biopsia renal percutánea: abordaje, caracterización de la técnica y resultados histopatológicos. Anales de Radiología México. 2018;17:30-6.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Marcia Solange de Oliveira Rotela, Alejandra Amarilla González, Lourdes Carolina Vázquez Jiménez, Marcelo Ramón Barrios Gini, Fernando Héctor Da Ponte González
This work is licensed under a Creative Commons Attribution 4.0 International License.